I'd be curious to see how comment nesting is handled UI wise for more than 6 comments. I am annoyed I can't reply to a comment when hitting that limit, but even with 6, it's already very hard to keep track of the conversation.
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Reddit is better on this, so far.
As abit commented, reddit has this done pretty well. Once you reach a maximum depth in the UI you can open another tree of comments from there.