Defying the biological law of aging, new research found that this weird mammal called the naked mole rats demonstrates that it can stay a long time without aging unlike humans who age!!!

in #science7 years ago (edited)

About Naked mole rat.

Why a naked mole rat? These rats area unit largely known for their longevity and additionally living healthily. It's botanical name is Heterocephalus glaber. They are one among the foremost blizzard mammals known to science. They barely have any hair more reason they're referred to as naked mole rats and have giant protrusive incisors. The skin of those rats are wrinkled, loose and brownish pink in color. They are usually housed at 28-30 degree celsius and 50-60% relative humidity.

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The social lifestyle of a naked mole rat.

These rats area are social and have cooperative behaviours. The study of their conduct is applicable to humans. It shows that these rats behaves like insect that some biologists findings enclosed these uncommon behaviour patterns ne'er before known to exist in rodents.

Which is:

One female chosen by ways still unknown becomes the queen of the colony and just like the queen in an exceedingly wasp colony, is that the solely breeding feminine within the community. The mole rats queen is the largest amongst all females within the colony. If the queen is off from the colony, a number of remaining females who grew larger will look forward in taking her place. One can prevail and become the new queen. The organisation of naked mole rat colony needs each male and females to perform several specialised chores, which has food carriers, nest builders, tunnel diggers and additionally nurse maids to the queen. How fascinating?

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The naked mole rat defying the biological law of aging.

These animals seldom get cancer and are immune to some kinds of pain, can also survive up to 18minutes in water without the help of oxygen. The primary study to shows the life histories of thousands of naked mole rats has found that their risk of death does not go up as they get older as it will for other species.

This is remarkably low mortality says Caleb finch a biogerontologist at the university of southern California in LA, wasn't concerned within the new study. At advanced ages their mortality rates remains not up to the other mammals that has been documented.source

Scientists have noted that these rats shows few signs of aging and much surpass the lifetime expected of a gnawing animal this size. Mice in captivity live at the most 4years and based on their size, naked mole rats wouldn't be expected to measure past 6 years. Instead some live on the far side 30years and even at that age breeding females keep fertile.

The secrets to longevity.

This longetivity traces back partly to exceptionally sturdy proteasome proteins within the naked mole rats that are unambiguously ready to survive a progressive onslaught of proteasome poisons. This resistance is permitted by a specific transferable chaperone containing cytosolic issue. This issue primarily hangs out with the proteasome, acting to modulate the garbage collector protein's activity.

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Scientists trying to modify the naked mole rat's cancer resistance for humans

Comparative scientist Rochelle Buffenstein has studied the animals for more than30 years and has quite virtually, collected a lifetime's value of knowledge. for every animal in her care, she recorded the date of birth Associate in Nursing once it's dead, checking whether or not it was killed throughout an experiment or given away to alternative researchers.

The proteasome stay active within the factor's gift and area unit what is more pushed to extend production of protease materials, enzymes that employment to interrupt the chemical bonds in sure proteins.

It's survival mechanism and metabolism. IMG_3533.JPG

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Animals with a subterranean way of life should manage both low oxygen stages (hypoxia) and raised carbon dioxide stages (hypercapnia). Naked mole-rats have a form of haemoglobin with an extremely excessive capacity to accumulate oxygen and so provide enough oxygen to the physique organs11.

Naked mole-rat brains are remarkably immune to hypoxia and maintain neurotransmission for much longer than mice all through bouts of low oxygen levels12. Hypoxia normally happens at some point of strokes and for this reason analyzing mechanisms underlying how the naked mole-rat copes with hypoxia may additionally lead a better knowledge of a way to treat stroke-related damage.

One possible effect of dwelling in hypercapnia is tissue acidification. That is because carbon dioxide generates carbonic acid upon touch with water in the frame, while humans in general discover acid painful (consider spilling juice or vinegar into an injured skin whilst cooking) and mice briefly lick their paw when receiving an injectionof acidic saline answer, bare mole-rats show no aversive reaction to acidic saline, even though they do show similar withdrawal responses to mice while tested for heat and pressure sensitivity13.

Conclusion:

In conclusion, this distinctive warm blooded creatures has been proven by researchers that it doesn't die of aging, however it eventually die which differentiates it from humans who goes through different vertebrate stages like embryos ,evolution of infant to adulthood and inevitably die of old age. This is to demonstrate that this warm blooded creature remains only the way it is conceived till after a period of time and dies without showing any signs of aging.

References

secrets of the longevity.

Their social lifestyle

It's survival mechanism and metabolism

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ok o. They should not overpopulate though!

Thanks for educating us on this