I read this blog a couple of times with great interest. The balance between inflammation and infection is one that has interested me for some time. Some years ago I began a protocol of daily, low-dose prednisone (3 mgs). I was very aware that it was kind of a devil's bargain, but sometimes that's the only bargain in town.
I'm familiar with the 'cytokine storm' that, paradoxically, is treated in severe flu with immune suppressive drugs--which also suppress inflammation. When I 'catch something' often my doctor will use a double-pronged approach: up the dose of prednisone and back it up with an antibiotic to fight secondary infection.
After reading your response to @gentleshaid I did some poking around to get COVID-relevant information on the tension between inflammation and infection. The article is 'old' (anything published before yesterday is old in this environment), published on March 25, 2020. However I do think the authors treat the inflammation/infection paradox well, in relation to COVID. Bottom line, I think: every patient is unique and medicine is an art. There are few fast rules. The smartest course for a patient is to pick a clever doctor who cares. And then, roll the dice :))
Here's the article
As usual, I am impressed with your knowledge, your ability to share it, and most of the sense of humanity that infuses everything you write.